Press Releases

When cloning mice, a little drop of blood'll do ya

26 Jun 2013—Since Dolly the sheep in 1996, reproductive cloning has continued to advance; nearly 20 different mammalian species have now been cloned. Researchers at the RIKEN BioResource Center in Tsukuba, Japan, have developed a unique cloning procedure using peripheral blood cells, which may be collected repeatedly from a single animal, facilitating preservation of infertile mouse strains.

  • BOR press release: English or Chinese.
  • BOR manuscript: Kamimura S, Inoue K, Ogonuki N, Hirose M, Oikawa M, Yo M, Ohara O, Miyoshi H, Ogura A. Mouse cloning using a drop of peripheral blood. Biol Reprod 2013; 89(2):24.

Maternal diabetes impairs methylation of imprinted gene in oocytes

20 Mar 2013—Offspring of diabetic mothers display a higher incidence of malformations and fetal death, which Dr. Zhao-Jia Ge et al. now link to impaired methylation of maternal imprinting gene Peg3.

  • BOR press release: English or Chinese.
  • BOR Open Access manuscript: Ge ZJ, Liang XW, Guo L, Liang QX, Luo SM, Wang YP, Wei YC, Han ZM, Schatten H, Suna QY. Maternal diabetes causes alterations of DNA methylation statuses of some imprinted genes in murine oocytes. Biol Reprod 2013; 88(5):117.

New assessment reveals value of second embryo biopsy for women of advanced maternal age

07 Nov 2012—An elegant new study confirms that the most commonly used method of screening for embryo abnormalities following in vitro fertilization (IVF) does accurately predict the success of embryo transplantation for younger women, but not necessarily for those of advanced maternal age.

  • BOR press release: English or Chinese.
  • BOR Open Access manuscript: Liu J, Wang W, Sun X, Liu L, Jin H, Li M, Witz C, Williams D, Griffith J, Skorupski J, Haddad G, Gill J. DNA microarray reveals that high proportions of human blastocysts from women of advanced maternal age are aneuploid and mosaic. Biol Reprod 2012; 87(6):148.

A pack of walnuts a day keeps the fertility specialist away?

15 Aug 2012—After eating 75 grams of walnuts every day for 12 weeks, healthy young men aged 21 to 35 saw increased sperm vitality, motility, and morphology, UCLA researchers report.

  • BOR press release.
  • BOR Open Access manuscript: Robbins WA, Xun L, FitzGerald LZ, Esguerra S, Henning SM, Carpenter CL. Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial. Biol Reprod 2012; 87(4):101.

How a low-protein diet predisposes offspring to adulthood hypertension

25 Jul 2012—New research finds that the high maternal testosterone levels associated with a low-protein diet in rats are caused by reduced activity of a testosterone inactivator, thereby allowing more testosterone to reach the fetus and increase the offspring's susceptibility to adulthood hypertension.

  • BOR press release.
  • BOR manuscript: Gao H, Yallampalli U, Yallampalli C. Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth. Biol Reprod 2012; 87(3):68.

Three types of fetal cells can migrate into maternal organs during pregnancy

6 Jun 2012—A pregnant woman's blood stream contains not only her own cells, but a small number of her child's, as well, and some of them remain in her internal organs long after the baby is born. Understanding the origin and identity of these cells is vital to understanding their potential effects on a mother's long-term health.

  • BOR press release.
  • BOR manuscript: Pritchard S, Wick HC, Slonim DK, Johnson KL, Bianchi DW. Comprehensive analysis of genes expressed by rare microchimeric fetal cells in the maternal mouse lung. Biol Reprod 2012; 87(2):42.

How neonatal plant estrogen exposure leads to adult infertility

2 May 2012—A new study examines how exposure to estrogenic chemicals in the womb or during childhood can have a long-term effect on female fertility. Limiting such exposures, including minimizing use of soy-based baby formula, would be a step toward maintaining female reproductive health.

  • BOR press release.
  • BOR manuscript: Jefferson WN, Padilla-Banks E, Phelps JY, Cantor AM, Williams CJ. Neonatal phytoestrogen exposure alters oviduct mucosal immune response to pregnancy and affects preimplantation embryo development in the mouse. Biol Reprod 2012; 87(1):10.

Can lactating tsetse flies model lactating mammals?

18 Apr 2012—An unprecedented study of intra-uterine lactation in the tsetse fly, published today in BOR's Papers-in-Press, reveals that an enzyme found in the fly's milk functions similarly in mammals, making the tsetse a potential model for lipid metabolism during mammalian lactation. Better yet, reduced levels of this enzyme led to poor health in offspring, leading the authors to suggest that targeting it could help decrease the tsetse population in Africa and reduce the incidence of sleeping sickness.

  • BOR press release.
  • BOR manuscript: Benoit JB, Attardo GM, Michalkova V, Takác P, Bohova J, Aksoy S. Sphingomyelinase activity in mother's milk is essential for juvenile development: a case from lactating tsetse flies. Biol Reprod 2012; 87(1):17.

Reproductive seasonality observed in male giant pandas

4 Apr 2012—A three-year study of giant pandas published today in BOR&arsquo;s Papers-in-Press reveals that reproductive seasonality exists not only in female pandas, but in male pandas as well. This new understanding will allow continued improvement of the captive panda management program and will one day assist in reintroducing pandas into the wild, the authors say.

  • BOR press release.
  • BOR manuscript: Aitken-Palmer C, Hou R, Burrell C, Zhang Z, Wang C, Spindler R, Wildt DE, Ottinger MA, Howard J. Protracted reproductive seasonality in the male giant panda (Ailuropoda melanoleuca) reflected by patterns in androgen profiles, ejaculate characteristics, and selected behaviors. Biol Reprod 2012; 86(6):195.

Biology of Reproduction moves to continuous online publication

6 Jan 2012—Starting this month, Biology of Reproduction is shifting its operations from print-focused publishing to continuous online publication. BOR-Papers in Press production will remain unchanged, but all final articles will now be posted on as they are completed, rather than being held until the issue is published. At the end of each month, the posted articles will be compiled as that month's issue. For more information, please see the full press release.