The Rising Stars in Reproductive Biology series is designed to introduce and highlight research from new investigators to the SSR membership and broader reproductive biology research community.
Each presentation will feature a 1-2 min introduction by an invited moderator, a 20 min talk by each Rising Star speaker, and 5-7 min for questions and answers.
Title: Storing Sugar in the Uterus: Glycogen Metabolism during Early Pregnancy
Speaker: Matthew Dean, PhD
The endometrium needs to regulate glucose availability precisely; too much or too little impairs decidualization and embryo development. We have shown that the epithelium and decidua store distinct pools of glucose as glycogen during early pregnancy. Thus, glycogen may represent a vital way to buffer glucose concentrations before and during implantation.
Title: Opportunities for Innovation in microTESE Negative Males With Non-Obstructive Azoospermia
Speaker: Ryan Flannigan, PhD
This talk will discuss the opportunities for innovation in microTESE negative non-obstructive azoospermic males. We will discuss opportunities for applying image-based machine learning for sperm identification following microTESE. We will also discuss a personalized and precision medicine framework aiming to overcome cellular dysfunction and promote regeneration of spermatogenesis using single cell sequencing, development of novel culture methods, use of human induced pluripotent stem cells and 3D bioprinting.