Opening Gates Virtual Symposia

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Opening Gates: New Methods and Approaches for Effective Contraception in Both Sexes


These webinars, sponsored by the Society for the Study of Reproduction (SSR), Frontiers in Reproduction (FIR), and the Bill & Melinda Gates Foundation, will focus on emerging technologies and approaches to male and female contraception.


Developing New Methods for Testing, Studying, and Delivering Contraception

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November 1, 2022

9-11 am EDT


Speakers:

Dr. Jianjun Sun, Associate Professor, Department of Physiology & Neurobiology, University of Connecticut, Storrs

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Title: Screening female contraceptive compounds using Drosophila ovulation model

Description: In my presentation, I will introduce the ovulation mechanism in Drosophila and describe the platform utilizing Drosophila ovulation to screen contraceptive compounds that can effectively inhibit follicle rupture.


Dr. Phil Santangelo, Associate Professor of Biomedical Engineering, Georgia Tech University & Emory University


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Title: Intravaginal delivery of mRNA encoded contraceptive antibodies




New Non-hormonal Contraceptive Targets

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November 8, 2022

6-8 pm EDT


Speakers:

Dr. Lonny R. Levin, Professor of Pharmacology, Weill Cornell Medical College



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Title: On-demand nonhormonal male contraception via ADCY10 inhibition

Description: Fast-acting sAC inhibitors with slow off-rates can provide safe, pre-coital, on-demand contraception for men which is nonhormonal, orally available, easily tolerated, fast-acting, and readily reversible.


Dr. Celia Santi, Associate Professor of OBGYN, Washington University School of Medicine in St. Louis



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Title: Targeting the sperm-specific K+ channel SLO3 for non-hormonal contraception.


Description: Identification of inhibitors of the sperm specific SLO3 K+ channel that can be developed into a non-hormonal class of female contraceptives that act by targeting sperm capacitation.







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